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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 2(56), p. 1093-1096, 2012

DOI: 10.1128/aac.00258-11

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Chromosomal Integration and Location on IncT Plasmids of the blaCTX-M-2 Gene in Proteus mirabilis Clinical Isolates

Journal article published in 2012 by Sohei Harada ORCID, Yoshikazu Ishii, Tomoo Saga, Yuichi Kouyama, Kazuhiro Tateda, Keizo Yamaguchi
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Analysis of five CTX-M-2-producing Proteus mirabilis isolates in Japan demonstrated that blaCTX-M-2 was located on the chromosome in four isolates and on IncT plasmids in three isolates, including two isolates that also carried the gene on the chromosome. In all four isolates with chromosomal blaCTX-M-2, ISEcp1 was responsible for the integration of the gene into the chromosome. Three different sites in the P. mirabilis genomic sequence were utilized as integration sites. Copyright © 2012, American Society for Microbiology. All Rights Reserved.