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American Thoracic Society, American Journal of Respiratory and Critical Care Medicine, 8(184), p. 904-912, 2011

DOI: 10.1164/rccm.201103-0520oc

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Telomere Length Is a Determinant of Emphysema Susceptibility

This paper is available in a repository.
This paper is available in a repository.

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Data provided by SHERPA/RoMEO

Abstract

Rationale: Germline mutations in the enzyme telomerase cause telomere shortening, and have their most common clinical manifestation in age-related lung disease that manifests as idiopathic pulmonary fibrosis. Short telomeres are also a unique heritable trait that is acquired with age.