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Wiley, Movement Disorders, 13(28), p. 1874-1877

DOI: 10.1002/mds.25581

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Pallidal stimulation for cervical dystonia does not correct abnormal temporal discrimination.

Journal article published in 2013 by Anna Sadnicka, Okka Kimmich, Claudia Pisarek, Diane Ruge, Joe Galea ORCID, Panagiotis Kassavetis, Isabel Pareés, Tabish Saifee, Anna Molloy, Kp Bhatia ORCID, David Bradley, Sean O'Riordan, Ludvic Zrinzo, Marwan Hariz, Patricia Limousin and other authors.
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This paper is available in a repository.

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Abstract

Background: We investigated whether clinical improvement observed after deep brain stimulation (DBS) of the globus pallidus internus (GPi) in cervical dystonia (CD) is paralleled by the normalisation of temporal discrimination thresholds (TDTs), a marker of abnormal sensory processing in CD. Methods: TDT was tested in 11 patients with CD after they received DBS and was compared with TDT scores from 24 patients with CD and a group of 61 controls. Results: A clear clinical response to GPi-DBS was demonstrated (total Toronto Western Spasmodic Torticollis Rating Scale scores fell from 50 to 18; P