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American Society for Microbiology, Journal of Clinical Microbiology, 7(34), p. 1825-1828, 1996

DOI: 10.1128/jcm.34.7.1825-1828.1996

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Molecular epidemiology of Mycobacterium tuberculosis strains isolated from different regions of Italy and Pakistan.

Journal article published in 1996 by Sechi La, Leonardo Antonio Sechi, Stefania Anna Lucia Zanetti, Giovanni Delogu ORCID, Barbara Montinaro, Alberto Sanna, Giovanni Fadda
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The use of the (GTG)5 oligonucleotide, a repetitive marker in the Mycobacterium tuberculosis chromosome, as a primer in association with an IS6110 outlooking primer has been successfully applied to a PCR-based fingerprinting method. This method classified 62 strains of M. tuberculosis, isolated from human immunodeficiency virus-seropositive and -seronegative patients in different regions of Italy and Pakistan, as having 53 different patterns. The results were compared with traditional IS6110 fingerprinting, by which 47 distinct patterns were observed.