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BioMed Central, Genome Biology, 8(11), p. R83

DOI: 10.1186/gb-2010-11-8-r83

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Cloud-scale RNA-sequencing differential expression analysis with Myrna

Journal article published in 2010 by Ben Langmead, Kasper D. Hansen ORCID, Jeffrey T. Leek
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract As sequencing throughput approaches dozens of gigabases per day, there is a growing need for efficient software for analysis of transcriptome sequencing (RNA-Seq) data. Myrna is a cloud-computing pipeline for calculating differential gene expression in large RNA-Seq datasets. We apply Myrna to the analysis of publicly available data sets and assess the goodness of fit of standard statistical models. Myrna is available from http://bowtie-bio.sf.net/myrna .