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BioMed Central, Genome Biology, 8(10), p. R83

DOI: 10.1186/gb-2009-10-8-r83

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Improved base calling for the Illumina Genome Analyzer using machine learning strategies

Journal article published in 2009 by Martin Kircher ORCID, Udo Stenzel, Janet Kelso
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract The Illumina Genome Analyzer generates millions of short sequencing reads. We present Ibis (Improved base identification system), an accurate, fast and easy-to-use base caller that significantly reduces the error rate and increases the output of usable reads. Ibis is faster and more robust with respect to chemistry and technology than other publicly available packages. Ibis is freely available under the GPL from http://bioinf.eva.mpg.de/Ibis/ .