This work studies the redox reactions of 2,5-dimercapto-1,3,4-thiadiazole (DMcT) on bare platinum single crystal electrodes and platinum electrodes modified by a thin film of poly(3,4-ethylenedioxythiophene) (PEDOT) using as electrolyte the ionic liquid 1-ethyl-2,3-dimethylimidazolium bis(trifluoromethylsulfonyl)imide ([Emmim][NTf2]). It was found that the redox reactions of DMcT are more reversible in [Emmim][NTf2] than in electrolytes dissolved in acetonitrile. Finally, it was found that the redox reactions of DMcT are surface sensitive on both bare and PEDOT modified Pt single crystal electrodes. ; APS is grateful for the scholarship “Estudiantes sobresalientes de posgrado” (UNAL), and to COLCIENCIAS for the national doctoral scholarship. MFS acknowledges support of UNAL (Research Project 19030). JMF acknowledges support for Generalitat Valenciana (Feder) through project PROMETEO/2009/045.