A durable slippery liquid-infused porous surface (SLIPS) omniphobic coating was developed that can be simply applied to various substrates to repel water, coffee, red wine and cooking oils. The coatings retain their slippery properties and omniphobicity even after extreme thermal, mechanical and chemical tests, including rapid cooling down to liquid nitrogen temperatures (−196 °C), heating 200 °C, knife cutting, 850 kPa newton meter pressing, Scotch tape peeling, exposure to acid, base and corrosive salt solutions (pH from 0 to 14), and neutralization on the SLIPS surface. This simple, low-cost and “ready to use” surface is believed to be useful for self-cleaning, anti-fouling, and anti-corrosion purposes potentially for large scale of industrial applications.