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Computed tomography myocardial perfusion vs 15O-water positron emission tomography and fractional flow reserve

Journal article published in 2016 by Michelle C. Williams, Saeed Mirsadraee, Marc R. Dweck, Nicholas W. Weir, Alison Fletcher, Christophe Lucatelli, Tom MacGillivray, Saroj K. Golay, Nicholas L. Cruden, Peter A. Henriksen, Neal Uren, Edwin J. R. van Beek, Graham McKillop, João A. C. Lima, John H. Reid and other authors.
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Objectives : Computed tomography (CT) can perform comprehensive cardiac imaging. We compared CT coronary angiography (CTCA) and CT myocardial perfusion (CTP) with 15O-water positron emission tomography (PET) and invasive coronary angiography (ICA) with fractional flow reserve (FFR). ; Methods : 51 patients (63 (61–65) years, 80 % male) with known/suspected coronary artery disease (CAD) underwent 320-multidetector CTCA followed by “snapshot” adenosine stress CTP. Of these 22 underwent PET and 47 ICA/FFR. Obstructive CAD was defined as CTCA stenosis >50 % and CTP hypoperfusion, ICA stenosis >70 % or FFR