The gut microbiome profile of HTN in the additional independent metagenomic analysis. (a) Bacterial α diversity (Shannon index) at the genus level is compared between control (n = 3) and HTN (n = 3) group. P value is from t test. (b) The genera abundance alteration in HTN patients is compared with the controls. Red represents more abundant, blue indicates less abundant. The genera marked with green points show a consistent trend in HTN compared with the results in stage 1 metagenomic analysis, while gray points represent the genera with inconsistent variation. (PDF 330 kb)