Oxford University Press, Neuro-Oncology, 12(18), p. 1644-1655, 2016
DOI: 10.1093/neuonc/now113
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Amplification of the epidermal growth factor receptor (EGFR) and its mutant EGFRvIII are among the most common genetic alterations in glioblastoma (GBM), the most frequent and most aggressive primary brain tumor.