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Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS), Clinical and Biomedical Research, 4(36), p. 254-256, 2016

DOI: 10.4322/2357-9730.68336

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ERK 1/2 activation does not contribute to increased survival mediated by bone marrow cells after 90% partial hepatectomy in Wistar rats

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We investigated the influence of bone marrow cells upon activation of ERK ½ in an animal model of 90% PH. Phosphorylated ERK 1/2 was evaluated by western blot. No differences were found between the groups. Thus, increased survival does not appear to be mediated by ERK 1/2 activation.Keywords: MAP Kinase Signaling System; stem cells; acute liver failure