An experimental campaign investigating the postulated Steam Generator Tube Rupture (SGTR) event, in relevant configurations for Heavy Liquid Metal Reactors (HLMRs), was carried out in the separate-effect facility LIFU5/Mod2, at ENEA CR Brasimone. Ten tests were performed injecting pressurized subcooled water into the reaction tank partially filled by Lead-Bismuth Eutectic alloy (LBE) at 400° C with a cover gas of argon at about 2 bar. Fast pressure transducers, thermocouples and strain gages provided high-quality measurement data for improving the phenomena understanding and supporting the development and validation phase of computer codes for SGTR numerical simulation. The experimental campaign is composed by two series of tests, characterized by different water pressure: 40 and 16 bar. The first two tests belonging to the low pressure experiments are presented, highlighting the pressurization time trends of the water injection tank, injection line and reaction vessel. The injected water mass flow rate and temperature trends in the reaction vessel were measured. The former test is the reference one and the latter was carried out for investigating the injection of water with higher sub-cooling. A post-test analysis of the two mentioned tests was carried out by SIMMER-III code. The pressure profile in the water injection tank was set as boundary condition of the calculation. The numerical analysis provided injection line and reaction tank pressurization in agreement with the experimental data. The lower water temperature test provided a better accordance with the measured data, due to the lower evaporation along the injection line. The SIMMER-III analysis also studied the water-LBE interaction from the volume fraction point of view and the energy released in the total reaction tank and in its cover gas. Copyright © 2016 by ASME.