Dissemin is shutting down on January 1st, 2025

Published in

American Society of Tropical Medicine and Hygiene, American Journal of Tropical Medicine and Hygiene, 1(84), p. 148-151, 2011

DOI: 10.4269/ajtmh.2011.10-0250

Links

Tools

Export citation

Search in Google Scholar

Iron Homeostasis in Mother and Child during Placental Malaria Infection

Journal article published in 2011 by S. van Santen, Susanne Van Santen, Q. de Mast, Quirijn de Mast ORCID, Erwin T. G. Wiegerinck, Adrian J. F. Luty, Dorine W. Swinkels, Andre J. A. M. Van der Ven
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Red circle
Preprint: archiving forbidden
Green circle
Postprint: archiving allowed
Upload
Orange circle
Published version: archiving restricted
Upload
Policy details
Data provided by SHERPA/RoMEO

Abstract

In malaria-endemic areas, iron deficiency and placental Plasmodium falciparum infection commonly coexist. In primigravidae and their newborns, hepcidin and other iron parameters were evaluated in groups and classified according to placental P. falciparum and maternal anemia status. Mothers had relatively high hepcidin levels considering their low iron status. In cord blood, levels of hepcidin, hemoglobin, and other iron parameters were also similar for groups. We conclude that maternal hepcidin is not significantly altered as a function of placental infection and/or anemia. Importantly, fetal hemoglobin and iron status were also unaffected, regardless of the presence of placental infection or maternal anemia.