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Wiley, Indoor Air, 3(27), p. 642-649, 2016

DOI: 10.1111/ina.12354

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Dermal uptake of phthalates from clothing: comparison of model to human participant results

Journal article published in 2016 by Glenn C. Morrison, {Charles J.} Weschler, Charles J. Weschler, Gabriel Bekö ORCID
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This paper is available in a repository.

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Abstract

In this research, we extend a model of transdermal uptake of phthalates to include a layer of clothing. When compared with experimental results, this model better estimates dermal uptake of diethylphthalate (DEP) and di-n-butylphthalate (DnBP) than a previous model. It also demonstrates that uptake is sensitive to both the gap between skin and clothing and the time clothing is allowed to adsorb phthalates. The model predictions are consistent with the observation that exposed clothing increases dermal uptake when compared with uptake observed in bare-skin participants. Extension of this model beyond the cotton-phthalate system will be challenging until data on partition coefficients are quantified for other combinations of SVOCs, fabric materials and environmental conditions.