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American Society of Tropical Medicine and Hygiene, American Journal of Tropical Medicine and Hygiene, 6(83), p. 1259-1261, 2010

DOI: 10.4269/ajtmh.2010.10-0422

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Pyrethroid Susceptibility in Natural Populations of the Anopheles punctulatus Group (Diptera: Culicidae) in Papua New Guinea

Journal article published in 2010 by John B. Keven, Edward K. Thomsen, Ivo Mueller, Peter M. Siba, Peter A. Zimmerman, Cara N. Henry-Halldin ORCID, Lisa J. Reimer
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The development of insecticide resistance has compromised mosquito control efforts in many parts of the world. Papua New Guinea (PNG) has a long history of dichlorodiphenyltrichloroethane (DDT) use and currently distributes pyrethroid-treated nets for malaria control. This study is the first to investigate the status of pyrethroid resistance in the Anopheles punctulatus group, the major malaria and filariasis vectors of PNG. The study used World Health Organization standard susceptibility bioassays to detect knockdown phenotypes and a novel nested polymerase chain reaction to detect the knockdown resistant (kdr) allele in these vectors. Our results show 100% susceptibility to pyrethroids in all populations surveyed and an absence of the kdr allele.