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American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 5(47), p. 1739-1741, 2003

DOI: 10.1128/aac.47.5.1739-1741.2003

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Burkholderia Is Highly Resistant to Human Beta-Defensin 3

Journal article published in 2003 by Hany Sahly, Sabine Schubert, Jürgen Harder ORCID, Peter Rautenberg, Uwe Ullmann, Jens Schröder, Rainer Podschun
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT The bactericidal activity of the novel beta-defensin hBD-3 against 28 species and 55 strains of gram-positive cocci and gram-negative fermentative and nonfermentative rods was tested. All strains proved to be highly or intermediately susceptible to hBD-3 (minimal bactericidal concentration [MBC], ≤50 μg/ml), except for Burkholderia cepacia , for all 23 tested strains of which MBCs were >100 μg/ml.