We propose and experimentally demonstrate THz photonic wireless communication systems with 16-QAM modulation in the 375-450 GHz band. The overall throughput reaches as high as 80 Gbit/s by exploiting four THz channels with 5 Gbaud 16-QAM baseband modulation per channel. We create a coherent optical frequency comb (OFC) for photonic generation of multiple THz carriers based on photo-mixing in a uni-travelling carrier photodiode (UTC-PD). The OFC configuration also allows us to generate reconfigurable THz carriers with low phase noise. The multiple-channel THz radiation is received by using a Schottky mixer based electrical receiver after 0.5 m free-space wireless propagation. 2-channel (40 Gbit/s) and 4-channel (80 Gbit/s) THz photonic wireless links with 16-QAM modulation are reported in this paper, and the bit error rate (BER) performance for all channels in both cases is below the hard decision forward error correction (HD-FEC) threshold of 3.8e-3 with 7% overhead. In addition, we also successfully demonstrate hybrid photonic wireless transmission of 40 Gbit/s 16-QAM signal at carrier frequencies of 400 GHz and 425 GHz over 30 km standard single mode fiber (SSMF) between the optical baseband signal transmitter and the THz wireless transmitter with negligible induced power penalty.