Showing SE alleles in HLA-DRB1 in relation to achieving DMARD-free sustained remission in RA patients in the Leiden EAC cohort. SE alleles were significantly associated with achieving DMARD-free sustained remission in 616 RA patients with HLA-DRB1 genotyping data (p = 2.72 × 10−4). The HR per SE allele for achieving remission was 0.57 (95 % CI = 0.42–0.77). The analysis was adjusted for age, gender, and inclusion period (as proxy for treatment strategy). (PDF 52 kb)