Sequencing quality. (A–C) Saturation analysis indicating adequate complexity and reproducibility of the mapped reads in the hDBS, rDBS and oDBS sample sets compared to the reference genome. (D–F) Calibration plot showing correct normalization of reads per window in the hDBS, rDBS and oDBS sample sets as a function of CpG density (chromosome 1 only). (PDF 380 kb)