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MOESM14 of Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Additional file 14. Expression of key genes from ES cell RNA-seq. The expression of Setdb1, all known H3K9 methyltransferases, representative pluripotency genes (Nanog, Zfp42 and Tet1), differentiation gene (Fgf5) and Xist, expressed as RPKM, for cells transduced with shSetdb1.4 (n = 2), shSetdb1.6 (n = 2) and Nons (n = 2), along a time course of differentiation of Xist ∆A/+ 129/CAST ES cells. Mean +s.e.m. The number of SNPs analysed within the exons of each gene is indicated (n). Mean +s.e.m. p-values determined by Student’s two-tailed t-test.