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Wiley Open Access, Clinical and Translational Allergy, 1(6), 2016

DOI: 10.1186/s13601-016-0113-z

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Allergen immunotherapy for IgE-mediated food allergy: protocol for a systematic review

Journal article published in 2016 by Sangeeta Dhami, Ulugbek Nurmatov, Giovanni Battista Pajno, Montserrat Fernandez-Rivas, Antonella Muraro, Graham Roberts, Cezmi Akdis, Montserrat Alvaro-Lozano, Kirsten Beyer, Carsten Bindslev-Jensen ORCID, George Toit, Wesley Burks, George Du Toit, Motohiro Ebisawa, Philippe Eigenmann ORCID and other authors.
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This paper is available in a repository.

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Abstract

Abstract Background The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food allergy. Methods We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion The findings from this review will be used to inform the development of recommendations for EAACIâ s Guidelines on AIT.