Additional file 1: Figure S1. The nucleotide sequences of 23 glycoside hydrolases. Three target sequences selected in this study are colored in red. Figure S2. Resistance of the recombinant cel7482 to high concentrations of ILs. The recombinant cel7482 was incubated with CMC at 37 °C for 30 min in 50 mM citrate–phosphate buffer (pH 7.0) supplemented with 20 % of [Emim]Cl, [Bmim]Cl or [Amim]Cl. The activity in reaction without ILs was set as 100 %. Figure S3. Alignment of cel7482 and cel3623 proteins. The amino acid sequences of cel7482 and cel3623 were aligned with ClustalX2.0.12. The identity or similarity of the residues is represented by (*), (:), and (.). The residues in the active site are colored in red. The different residues in the entryway of active site between cel7482 and cel3623 are colored in green and underline. Figure S4. Alignment of cel36 and 3PZT proteins. The amino acid sequences of cel36 and 3PZT were aligned with ClustalX2.0.12. The identity or similarity of the residues is represented by (*), (:), and (.). The residues in the active site are colored in red.