Additional file 3: Figure S3. of Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development
Published in 2016 by
Anne Rochtus,
Raf Winand,
Griet Laenen,
Elise Vangeel,
Benedetta Izzi,
Christine Wittevrongel,
Yves Moreau,
Carla Verpoorten,
Katrien Jansen,
Chris Van Geet,
Kathleen Freson
Abstract
Mean methylation of SOX18 for MMC patients and controls according to MTHFR 677 C>T genotype by Sequenom EpiTYPER. Boxplot representing the methylation pattern of MMC patients and controls divided according to MTHFR 677 C>T genotype with box = 25th and 75th percentiles; bars = min and max values. The mean methylation level of each group is shown above the plot. (TIFF 337 kb)