Supplementary Figures. Figure S1 shows the non-normalised mean absolute numbers of SNVs in a triplet mutation context, plus the triplet frequencies used for normalisation; Figure S2 is a sequence context analysis of GA > GT cisplatin-induced mutations; Figure S3 shows the wider sequence context of SNVs induced by cisplatin and cyclophosphamide; Figure S4 shows cisplatin-induced dinucleotide deletions; Figure S5 is an analysis of mutation clustering between samples; Figure S6 contains triplet SNV mutation spectra for each individual sequenced clone. (PDF 3484 kb)