Dissemin is shutting down on January 1st, 2025

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Lippincott, Williams & Wilkins, Annals of Surgery, 1(242), p. 92-100, 2005

DOI: 10.1097/01.sla.0000167853.04171.bb

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Clinicopathologic Analysis of Early Ampullary Cancers With a Focus on the Feasibility of Ampullectomy

This paper is available in a repository.
This paper is available in a repository.

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Abstract

The clinicopathologic features of early ampullary cancer (pTis, pT1 cancer) were investigated to determine the indications for ampullectomy. Despite a fairly good prognosis, a substantial number of early ampullary cancers had risk factors for failure after ampullectomy (lymph node metastasis, perineural invasion, common bile duct or pancreatic duct mucosal involvement). Pancreatoduodenectomy should be preferably performed for adequate radical resection even in early ampullary cancer, and ampullectomy should be reserved for pTis cancer or pT1 cancer sized 1.0 cm or less with a high operative risk.