The antimicrobial and wear behaviour of metallic glass composites corresponding to the Cu(ZrAl) system with x = (0, 3 and 6) has been studied. The three compositions consist of crystalline phases embedded in an amorphous matrix and they exhibit crystallinity increase with increasing Cu content, i.e., decrease of the glass-forming ability. The wear resistance also increases with the addition of Cu as indirectly assessed from H/E and H/E parameters obtained from nanoindentation tests. These results are in agreement with scratch tests since for the alloy with highest Cu content, i.e., CuZrAl, reveals a crack increase, lower pile-up, prone adhesion wear in dry sliding and higher scratch groove volume to pile-up volume. Samples with higher Cu content revealed higher hydrophilicity. Time-kill studies revealed higher reduction in colony-forming units for E. coli (gram-negative) and B. subtilis (gram-positive) after 60 min of contact time for the CuZrAl alloy and all the samples achieved a complete elimination of bacteria in 250 min. ; V.M.V. and S.G. acknowledge research support from Northumbria University. Partial financial support from 2014-SGR-1015 (Generalitat de Catalunya), and MAT2014-57960-C3-1-R (from MINECO, co-financed by FEDER) is acknowledged. We acknowledge G. Wells and the Smart Materials and Surfaces Laboratory from Northumbria University for the support with the sessile drop tests. ; Peer Reviewed