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Not all patients with impaired fasting glucoase require the same management: development of a nomogram for predicting regression from impaired fsating glucose to nomoglycaemia for primary care patients in Hong Kong

Proceedings article published in 2016 by Yte Yu ORCID, Y. Guo, Ckh Wong, Sy Ho, Clk Lam
This paper was not found in any repository; the policy of its publisher is unknown or unclear.
This paper was not found in any repository; the policy of its publisher is unknown or unclear.

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Abstract

Conference Theme: A Flourishing Community - Our Vision in Primary Care ; Introduction: Impaired fasting glucose (IFG) is a commonly encountered risk factor for diabetes mellitus (DM) in the primary care setting. Individuals with IFG are recommended for regular oral glucose tolerance test (OGTT) to monitor progression to DM and lifestyle interventions to prevent development of DM, which represent additional burden for these individuals and the healthcare system. Since the IFG group is heterogenous with 25% subjects progressing to DM, 25% regressing to normoglycaemia and 50% remaining in the group over time, identifying factors associated with early regression to normoglycaemia can be a potentially time- and cost-saving strategy to guide resource allocation for IFG patients. This study aims to evaluate the determinants of regression from IFG to normoglycaemia based on the fasting plasma glucose (FPG) levels and other non-invasive variables, and to develop and validate a nomogram that can be used to predict the regression in primary care clinical settings. Methods: A total of 1,197 IFG individuals were invited to repeat a FPG test and 75-gram 2-hour-OGTT to determine the glycemic change within a period of 18 months. Normoglycaemia was defined as FPG