In Hong Kong, early intervention for psychosis program (EASY) was developed in 2001 as a territory wide service. It provided 2-year case management service to first-episode psychosis patients of age 15-25. There are convincing evidence on the short-term benefits of early intervention (EI) service for psychosis, including the EASY program in Hong Kong. However , long-term outcome studies are limited with inconsistent results. Current study has examined the 10-year outcomes of patients with first-episode psychosis who received two-year EI service (EASY) compared with those who received standard care (SC) in Hong Kong using historical control design. Consecutive patients who received EI service in the whole territory between 1st July 2001 and 30th June 2002, and with diagnosis of Schizophrenia-spectrum diagnosis, were identified and matched with patients who received SC first presented to the public psychiatric service from 1st July 2000 and 30th June 2001. 148 matched pairs of patients were identified. Cross-sectional information on symptomatology and functioning was obtained through semi-structured interview; longitudinal information on admission, functioning, suicidal attempts, mortality and relapse over 10 years was obtained from clinical database. 70.3% (N=104) of SC and 74.3% (N=110) of EI patients were successfully interviewed. Results suggested that EI patients had fewer number (OR=1.56, X2=15.64, p