Published in
Nature Research, Nature Reviews Urology, 12(7), p. 650-652, 2010
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- ORCID
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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New answers prompt new questions regarding cell of origin
Journal article published in 2010 by
Angelo M. De Marzo,
William G. Nelson,
Charles J. Bieberich 
,
Srinivasan Yegnasubramanian
,
Srinivasan Yegnasubramanian
This paper is made freely available by the publisher.
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Abstract
Controversies remain regarding the precise cell type from which prostate cancers originate. In the last 2 years, two separate studies have arrived at apparently conflicting models for the cell type involved in prostate cancer initiation. However, these results are not mutually exclusive: there are potential solutions, and alternative views on the initiating cell derivation of prostate tumors also exist.