Reliable information of morbidity and mortality from venomous injuries are essential for effective state and national health policies for the prevention and treatment of this injury. Brazil and Australia are known for the numerous venomous animals that reside on these continents from snakes, scorpions to spiders. Nevertheless the burden of this injury is very different. Envenomation injury in Brazil is a notifiable event reported by the hospital. These notifications have demonstrated a burden of 206 per 100,000 people bitten or stung annually, whereas Australia demonstrates 36 per 100,000 hospitalisations per year attributed to a bite or sting. The overall health frameworks between the two countries are similar. Brazil has an established national health surveillance system, principles and guidelines to support the epidemiological understanding of injuries and accidents caused by envenomation, the logistical capacity to delivery timely medications and equipment and the education system to produce informed professionals. We will discuss the surveillance, health system framework to compare and contrast the two countries in order to identify areas of overlap and lessons learned between the two countries.