During the last decades, several climate-modelling studies have forecasted a decrease in precipitation inSouthern Amazonia, projecting scenarios of a drier Amazon for the future in relation with deforestation (or forest cover).In this area, only a limited number of analyses using forest cover data and rainfall time series have considered the transitionalzones between the Amazon Forest and the Cerrado biome. In this work, we evaluated whether forest cover and rainfall patternsare correlated. The analysis encompassed rainfall times series from 207 rain gauges during the 1971–2010 period, and forestcover data acquired from LANDSAT5 satellite images. The results indicate that, at local level (1–15 km), both seasonal andannual precipitation values are not correlated to forest cover, whereas at the regional scale (30–50 km) contrasting to annualvalues, significant correlation occurs between forest cover and seasonal precipitation. Additionally, the study suggests that thelarger the forest areas, the greater the probabilities of those influencing precipitation at regional scale, in opposite direction tothe observed local level effects.