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Rockefeller University Press, Journal of Cell Biology, 1(213), p. 2131OIA66
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Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer
Journal article published in 2016 by
Lucia D'Amico,
Lucia D’Amico,
Sahil Mahajan,
Aude-Hélène Capietto,
Zhengfeng Yang,
Ali Zamani,
Biancamaria Ricci,
David B. Bumpass 
,
Melissa A. Meyer,
Xinming Su ,
Andrea Wang-Gillam,
Katherine Weilbaecher,
Sheila Ann Stewart,
David G. DeNardo,
Roberta Faccio
,
Melissa A. Meyer,
Xinming Su ,
Andrea Wang-Gillam,
Katherine Weilbaecher,
Sheila Ann Stewart,
David G. DeNardo,
Roberta Faccio
This paper is available in a repository.
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Abstract
D’Amico et al. show that Dkk1 exerts immune-suppressive effects by directly targeting β-catenin in murine and human MDSCs and promoting their activation in cancer.