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MDPI, International Journal of Molecular Sciences, 10(15), p. 17901-17919, 2014

DOI: 10.3390/ijms151017901

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Platelets: Still a Therapeutical Target for Haemostatic Disorders

Journal article published in 2014 by Reinaldo Barros Geraldo, Plínio Cunha Sathler ORCID, André Luiz Lourenço, Max Seidy Saito, Lucio M. Cabral, Pabulo Henrique Rampelotto, Helena Carla Castro
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designing new antithrombotic agents. The option of new biotechnological sources is also explored.