Purpose.Administration of supplemental oxygen is common in paediatric intensive care. We explored the current practice of oxygen administration using a case vignette in paediatric intensive care units (PICU) in the united kingdom.Methods.We conducted an online survey of Paediatric Intensive Care Society members in the UK. The survey outlined a clinical scenario followed by questions on oxygenation targets for 5 common diagnoses seen in critically ill children.Results.Fifty-three paediatric intensive care unit members from 10 institutions completed the survey. In a child with moderate ventilatory requirements, 21 respondents (42%) did not follow arterial partial pressure of oxygen (PaO₂) targets. In acute respiratory distress syndrome, cardiac arrest, and sepsis, there was a trend to aim for lower PaO₂as the fraction of inspired oxygen (FiO₂) increased. Conversely, in traumatic brain injury and pulmonary hypertension, respondents aimed for normal PaO₂even as the FiO₂increased.Conclusions.In this sample of clinicians PaO₂targets were not commonly used. Clinicians target lower PaO₂as FiO₂increases in acute respiratory distress syndrome, cardiac arrest, and sepsis whilst targeting normal range irrespective of FiO₂in traumatic brain injury and pulmonary hypertension.