Published in

Elsevier, Journal of Allergy and Clinical Immunology, 4(138), p. 1071-1080, 2016

DOI: 10.1016/j.jaci.2016.03.018

Links

Tools

Export citation

Search in Google Scholar

Identification of a new locus at 16q12 associated with time to asthma onset

Journal article published in 2016 by Chloé Sarnowski ORCID, Pe Sugier, Raquel Granell ORCID, Debbie Jarvis, Mh Dizier ORCID, Markus Ege ORCID, Medea Imboden, Catherine Laprise, Ek Khusnutdinova, Mb Freidin, Wo Cookson, Miriam Moffatt, Mark Lathrop, Valérie Siroux ORCID, Lm Ogorodova and other authors.
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Green circle
Preprint: archiving allowed
Upload
Orange circle
Postprint: archiving restricted
Upload
Red circle
Published version: archiving forbidden
Policy details
Data provided by SHERPA/RoMEO

Abstract

Background Asthma is a heterogeneous disease in which age of onset plays an important role. Objective We sought to identify the genetic variants associated with time to asthma onset (TAO). Methods We conducted a large-scale meta-analysis of 9 genome-wide association studies of TAO (total of 5462 asthmatic patients with a broad range of age of asthma onset and 8424 control subjects of European ancestry) performed by using survival analysis techniques. Results We detected 5 regions associated with TAO at the genome-wide significant level (P