Open questions: how does Wolbachia do what it does?
Journal article published in 2016 by
Francis M. Jiggins 
This paper is made freely available by the publisher.
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Abstract
Abstract A common symbiont of insects, the bacterium Wolbachia has been implicated in phenomena as diverse as sex determination, pathogen defence and speciation and is being used in public health programs to prevent mosquitoes transmitting disease. Despite decades of research, we know remarkably little about how it exerts its effects.