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Elsevier, Journal of Investigative Dermatology, 1(130), p. 12-14, 2010

DOI: 10.1038/jid.2009.332

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Melanoma Molecular Subtypes: Unifying and Paradoxical Results

Journal article published in 2010 by Nancy E. Thomas, Peter A. Kanetsky, Colin B. Begg, Kathleen Conway, Marianne Berwick ORCID
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This paper is available in a repository.

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Abstract

In this issue, Hacker and colleagues provide further evidence that molecular subtypes of malignant melanoma may develop along divergent pathways. The authors did not find an association between somatic BRAF-mutant melanoma and germline melanocortin-1 receptor (MC1R) gene status. We discuss this seeming paradox in light of previous studies demonstrating strong associations.