Objective: Cadherins are key components of the adherens junction complexes. Thus, they are responsible for cell-cell adhesion as well as cell motility. Especially in epithelial carcinomas, loss of E-cadherin contributes to diminished cell polarity and promotes epithelial-mesenchymal transition (EMT).[for full text, please go to the a.m. URL] ; SeriesInformation ; 66. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)