Bentham Science Publishers, Protein and Peptide Letters, 6(16), p. 623-630
DOI: 10.2174/092986609788490186
Full text: Unavailable
Since their recent identification, eukaryotic Hsp70 nucleotide exchange factors (NEFs) have gained increasing interest due to their engagement in vital cellular processes. Here, I summarize our current knowledge of their mechanisms of action, regulations and cellular functions as well as their relevance for human diseases such as cystic fibrosis or amyloidoses.