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Wiley, Movement Disorders, 2(27), p. 305-307

DOI: 10.1002/mds.24026

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Eye symptoms in relatives of patients with primary adult-onset dystonia

Journal article published in 2011 by Giovanni Defazio ORCID, Giovanni Abbruzzese, Maria Stella Aniello, Maria Stella Aniello, Aniello Ms, Roberta Di Fede, Marcello Esposito, Giovanni Fabbrini, Paolo Girlanda, Rocco Liguori, Lucio Marinelli ORCID, Davide Martino, Francesca Morgante, Lucio Santoro, Michele Tinazzi ORCID and other authors.
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

METHODS: Using a validated questionnaire, we screened eye symptoms (burning sensation, grittiness, dry eye) in 333 first-degree relatives of 140 probands with different forms of primary adult-onset dystonia, 208 healthy subjects, and 293 patients with primary blepharospasm. RESULTS: The rate of eye symptoms was similar in the relatives of focal dystonia patients and in healthy subjects (adjusted HR, 1.1; 95\% CI, 0.7-1.7; P = .69), thus suggesting a common origin of eye symptoms in both groups. A higher rate was observed in blepharospasm patients (adjusted HR, 2; 95\% CI, 1.4-2.9; P