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Oxford University Press, The Journal of Infectious Diseases, 4(211), p. 623-634, 2014

DOI: 10.1093/infdis/jiu487

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Severe malarial thrombocytopenia : a risk factor for mortality in Papua, Indonesia

Journal article published in 2014 by Daniel A. Lampah, Tsin W. Yeo, Michael Malloy, Enny Kenangalem, Nicholas M. Douglas, Donny Ronaldo, Paulus Sugiarto, Julie A. Simpson ORCID, Jeanne Rini Poespoprodjo, Nicholas M. Anstey, Ric N. Price
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background: The significance of thrombocytopenia to the morbidity and mortality of malaria is poorly defined. We compared the platelet counts and clinical correlates of patients with and those without malaria in southern Papua, Indonesia. Methods: Data were collated on patients presenting to a referral hospital between April 2004 and December 2012. Results: Platelet measurements were available in 215 479 patients (23.4%), 66 421 (30.8%) of whom had clinical malaria. Patients with Plasmodium falciparum monoinfection had the lowest platelet counts and greatest risk of severe thrombocytopenia (platelet count,