Published in

American Society of Hematology, Blood, 20(127), p. 2451-2459, 2016

DOI: 10.1182/blood-2015-12-688705

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Comprehensive mutational profiling of core binding factor acute myeloid leukemia

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Data provided by SHERPA/RoMEO

Abstract

Key Points Recurrent mutations in chromatin modifiers and cohesin were observed in t(8;21) AML, but not inv(16) AML. t(8;21) AML patients with mutations in kinase signaling plus chromatin modifiers or cohesin members had the highest risk of relapse.