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Dove Press, Clinical Interventions in Aging, p. 307

DOI: 10.2147/cia.s102577

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Effectiveness and safety of oxycodone/naloxone in the management of chronic pain in patients with systemic sclerosis with recurrent digital ulcers: two case reports

Journal article published in 2016 by Francesca Ingegnoli ORCID, Nicola Ughi ORCID, Chiara Crotti
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Digital ulcers (DUs) are a severe and frequent clinical feature of patients with systemic sclerosis (SSc). The presence of DUs may cause severe pain and often lead to impairment of patient’s functional activities and health-related quality of life. Moreover, poor patient cooperation during the wound care procedure due to pain may be associated with a negative outcome of DU healing. Therefore, pain management has a key role in patients with SSc. These two case reports describe the effectiveness and safety of oxycodone/naloxone in patients with SSc complicated by painful chronic DUs. Such a therapy has provided pain relief and consequently an increased compliance during redressing wounds.