<b><i>Background:</i></b> A scientific presentation is a professional way to share your observation, introduce a hypothesis, demonstrate and interpret the results of a study, or summarize what is learned or to be studied on the subject. <b><i>Presentation Methods:</i></b> Commonly, presentations at major conferences include podium (oral, platform), poster or lecture, and if selected one should be prepared to PRESENT: <under>P</under>lan from the start (place integral parts of the presentation in logical sequence); <under>R</under>educe the amount of text and visual aids to the bare minimum; <under>E</under>lucidate (clarify) methods; <under>S</under>ummarize results and key messages; <under>E</under>ffectively deliver; <under>N</under>ote all shortcomings, and <under>T</under>ransform your own and the current thinking of others. We provide tips on how to achieve this. <b><i>Presentation Results:</i></b> After disclosing conflicts, if applicable, start with a brief summary of what is known and why it is required to investigate the subject. State the research question or the purpose of the lecture. For original presentations follow a structure: Introduction, Methods, Results, Conclusions. Invest a sufficient amount of time or poster space in describing the study methods. Clearly organize and deliver the results or synopsis of relevant studies. Include absolute numbers and simple statistics before showing advanced analyses. Remember to present one point at a time. Stay focused. Discuss study limitations. In a lecture or a podium talk or when standing by your poster, always think clearly, have a logical plan, gain audience attention, make them interested in your subject, excite their own thinking about the problem, listen to questions and carefully weigh the evidence that would justify the punch-line. <b><i>Conclusions:</i></b> Rank scientific evidence in your presentation appropriately. What may seem obvious may turn erroneous or more complex. Rehearse your presentation before you deliver it at a conference. Challenge yourself to dry runs with your most critically thinking colleagues. When the time comes, ace it with a clear mind, precise execution and fund of knowledge.