Published in
Ivyspring International Publisher, International Journal of Medical Sciences, 3(13), p. 206-219
DOI: 10.7150/ijms.13268
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Dietary Flaxseed Mitigates Impaired Skeletal Muscle Regeneration: in Vivo, in Vitro and in Silico Studies
Journal article published in 2016 by
Felicia Carotenuto,
Alessandra Costa,
Maria Cristina Albertini,
Marco Bruno Luigi Rocchi 
,
Alexander Rudov,
Dario Coletti ,
Marilena Minieri,
Paolo Di Nardo,
Laura Teodori
,
Alexander Rudov,
Dario Coletti ,
Marilena Minieri,
Paolo Di Nardo,
Laura Teodori
This paper is made freely available by the publisher.
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Abstract
Diets enriched with n-3 polyunsaturated fatty acids (n-3 PUFAs) have been shown to exert a positive impact on muscle diseases. Flaxseed is one of the richest sources of n-3 PUFA acid α-linolenic acid (ALA). The aim of this study was to assess the effects of flaxseed and ALA in models of skeletal muscle degeneration characterized by high levels of Tumor Necrosis Factor-α (TNF).