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BioMed Central, BMC Neuroscience, 1(13), 2012

DOI: 10.1186/1471-2202-13-85

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Disturbed oscillatory brain dynamics in subcortical ischemic vascular dementia

Journal article published in 2012 by Elisabeth Cw W. van Straaten, Willem de Haan ORCID, Hanneke de Waal, Philip Scheltens, Wiesje M. van der Flier, Frederik Barkhof, Ted Koene, Cornelis J. Stam
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Background White matter hyperintensities (WMH) can lead to dementia but the underlying physiological mechanisms are unclear. We compared relative oscillatory power from electroencephalographic studies (EEGs) of 17 patients with subcortical ischemic vascular dementia, based on extensive white matter hyperintensities (SIVD-WMH) with 17 controls to investigate physiological changes underlying this diagnosis. Results Differences between the groups were large, with a decrease of relative power of fast activity in patients (alpha power 0.25 ± 0.12 versus 0.38 ± 0.13, p = 0.01; beta power 0.08 ± 0.04 versus 0.19 ± 0.07; p