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American Society for Microbiology, Journal of Bacteriology, 18(194), p. 5144-5145, 2012

DOI: 10.1128/jb.01099-12

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Genome Sequence of a Neisseria meningitidis Capsule Null Locus Strain from the Clonal Complex of Sequence Type 198

Journal article published in 2012 by Sabine Schork, Andreas Schlüter ORCID, Jochen Blom, Susanne Schneiker-Bekel, Alfred Pühler, Alexander Goesmann, Matthias Frosch, Christoph Schoen
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACTNeisseria meningitidisis a commensal and accidental pathogen exclusively of humans. Although the production of polysaccharide capsules is considered to be essential for meningococcal virulence, there have been reports of constitutively unencapsulated strains causing invasive meningococcal disease (IMD). Here we report the genome sequence of a capsule null locus (cnl) strain of sequence type 198 (ST-198), which is found in half of the reported cases of IMD caused bycnlmeningococcal strains.