A new species of the hippolytid shrimp genus Lebbeus White, 1847 is described from the Von Damm Vent Field (VDVF) on the Mid-Cayman Spreading Centre, Caribbean Sea, at 2294 m water depth. Lebbeus virentova sp. nov. is defined and illustrated from seven specimens, with brief notes on its distribution and habitat. Molecular phylogenetic data from the COI mDNA region are used to analyse the species’ phylogenetic position, and its morphology is compared with previously described species. This new species represents the second family of caridean shrimp to be reported from the VDVF. Lebbeus virentova sp. nov. is the eighth member of the genus to be described from hydrothermal vents and appears to be the first hippolytid shrimp at a vent field known from outside the Pacific Ocean.