Dissemin is shutting down on January 1st, 2025

Links

Tools

Export citation

Search in Google Scholar

The determinants of serum vitamin D levels in participants in a melanoma case–control study living in a temperate climate

Journal article published in 2011 by John R. Davies, D. Timothy Bishop, Yu-Mei Chang, Helen Snowden, May Chan, Susan Leake, Birute Karpavicius, Sue Haynes, Kairen Kukalizch, Juliette Randerson-Moor, Faye Elliott, Julian Barth, Peter A. Kanetsky, Mark Harland, D. Timothy Bishop and other authors.
This paper is available in a repository.
This paper is available in a repository.

Full text: Download

Question mark in circle
Preprint: policy unknown
Upload
Question mark in circle
Postprint: policy unknown
Upload
Question mark in circle
Published version: policy unknown
Upload

Abstract

Background : We report the determinants of serum levels of vitamin D in a UK melanoma case–control study benefitting from detailed exposure and genotyping data. ; Methods : Sun exposure, supplemental vitamin D, and SNPs reported to be associated with serum levels were assessed as predictors of a single serum 25-hydroxyvitamin D3 measurement adjusted for season, age, sex, and body mass index. ; Results : Adjusted analyses showed that vitamin D levels were sub-optimal especially in the sun-sensitive individuals (−2.61 nmol/L, p = 0.03) and for inheritance of a genetic variant in the GC gene coding for the vitamin D-binding protein (−5.79 for heterozygotes versus wild type, p =